香港股票分析師協會主席鄧聲興:癌症疫苗申專利或有利長江生科價值提升
香港股票分析師協會主席鄧聲興博士近日在文匯報推介公司股票:
其主要觀點為:
長江生命科技(00775.HK)近期公佈,集團旗下針對滋養層細胞表面抗原2「TROP2」的新型癌症疫苗,在臨牀前階段實驗室測試中取得良好的早期成果,並已向香港知識產權署提交原授標準專利申請,及向美國專利商標局提交相關臨時專利申請。
資料顯示,TROP2是治療性標靶癌症疫苗,該專利申請的疫苗構建體在三陰性乳腺癌及結直腸癌臨牀前研究,被發現能大幅度抑制腫瘤生長,其中三陰性乳腺癌動物試驗結果展現抗癌效能。數據顯示,在涉及超過170只小鼠的TROP2候選疫苗在五項臨牀前研究中,四項研究顯示達到100%的腫瘤生長抑制,而剩餘一項研究顯示約80%的抑制率。
從技術端來看,TROP2疫苗有望成為首個針對亞洲高發癌種的根治性療法,聚焦亞洲高發、預後差的癌種,可有效填補亞洲高發癌種的需求空白,臨牀需求迫切。同時,其潛在適應症延展性強,可覆蓋肺癌、胰腺癌等多癌種,商業化價值有望提升。治療場景方面,從術後防復發切入,突破傳統末線治療侷限,有望改善患者生存率與生活質量。如步入成熟的臨牀階段,將有望造福更多病患,或有望成為公司未來的重要產品,商業化後亦可為集團帶來潛在價值。
長江生命科技多年專注研發,現時擁有多個進入臨牀階段的醫療研發項目管線,R&D產品線被嚴重低估,未來或可實現價值釋放,為公司帶來更多成本入賬和實質性業績貢獻。同時,憑藉旗下保健品業務提供的穩定資金,集團具備充沛的現金流,可持續支持更多研發推進。2024年,公司臨牀試驗及實驗室費用同比增長近60%達1.61億港元,顯示出集團對研發的高度重視和持續投入。
此外,集團近期在與多家國際投行間的資本市場密會上表示,將「全面開放所有戰略選項」,包括但不限於戰略合作、合資公司設立、業務分拆上市以及併購整合等多元化資本運作方式,以最大化股東價值。相信都可獲得更多資金支持,有望加強集團在癌症疫苗領域的技術積累,亦顯示集團有益擴充更多靈活的資本獲取渠道。料未來亦可考慮分拆旗下產品線以18A上市,連同潛在的戰略合作的益處等,或有望為集團帶來更多發展空間。
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