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歌禮制藥-B(01672.HK):小分子口服GLP-1R激動劑ASC30美國13周IIa期研究完成首批肥胖或超重受試者給藥

格隆匯7月3日丨歌禮制藥-B(01672.HK)發佈公告,小分子口服GLP-1受體(GLP-1R)激動劑ASC30治療肥胖症的美國13周IIa期研究(NCT07002905)已完成首批受試者給藥,受試者爲肥胖人羣或伴有至少一種體重相關合併症的超重人羣。由歌禮自主研發的ASC30是首款也是唯一一款既可每日一次口服也可每月一次皮下注射的用於治療肥胖症的在研小分子GLP-1R偏向激動劑。

“我們很高興ASC30美國13周IIa期研究進度提前,已於6月開展受試者篩選並於近日完成了首批受試者給藥。”歌禮創始人、董事會主席兼首席執行官吳勁梓博士表示,“預計於2025年第四季度獲得該項IIa期研究的頂線數據,對此我們充滿期待。作爲一種小分子藥物,如獲批,ASC30有望提供每日一次口服和每月一次皮下注射兩種給藥選擇治療肥胖症。”

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