魯抗醫藥(600789.SH):非布司他獲得化學原料藥上市申請批准通知書
格隆匯6月3日丨魯抗醫藥(600789.SH)公佈,公司收到國家藥品監督管理局頒發的關於非布司他(稱“該藥品”)的《化學原料藥上市申請批准通知書》(通知書編號:2024YS00481),該藥品批准上市申請。
非布司他為2-芳基噻唑衍生物,是一種黃嘌呤氧化酶抑制劑,通過抑制尿酸合成降低血清尿酸濃度,可作為痛風患者的一線降尿酸藥物。與已有的降尿酸藥物不同,非布司他不僅對牛磺酸的合成沒有抑制作用,且不影響尿酸在腎臟中的排泄,而是通過調節體內尿酸的產生來實現降尿酸的效果。
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