和譽-B(02256.HK)治療胰腺癌藥物臨床試驗完成首例患者給藥
和譽-B(02256.HK)公布,其附屬和譽醫藥已在組長單位上海交通大學醫學院附屬仁濟醫院完成「一項評估ABSK021聯合化療以及ABSK021聯合化療和特瑞普利單抗治療晚期胰腺癌患者有效性和安全性的多中心、開放標籤的II期臨床研究(方案編號:ABSK021-202)」首例患者給藥。
公司指出,Pimicotinib (ABSK021)是和譽醫藥獨立自主研發的一款全新口服、高選擇性、高活性CSF1R小分子抑制劑。研究表明,阻斷CSF1/CSF1R信號通路可調節和改變巨噬細胞功能,有助於重塑腫瘤免疫抑制性微環境。
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