舒泰神(300204.SZ):STSA-1001注射液用於治療疼痛(包括癌痛、骨關節炎疼痛和慢性腰背痛)的臨牀試驗申請獲得受理
格隆匯10月24日丨舒泰神(300204.SZ)公佈,公司收到了國家藥品監督管理局行政許可文書《受理通知書》,國家藥品監督管理局同意受理舒泰神提交的關於STSA-1001注射液用於治療疼痛(包括癌痛、骨關節炎疼痛和慢性腰背痛)的臨牀試驗申請。
STSA-1001注射液是一種重組抗NGF的全人源IgG1單克隆抗體注射液。該抗體可以有效阻斷NGF與其受體的結合,從而在疼痛疾病中有效抑制NGF信號通路,減少因過度神經支配而引起的神經性疼痛;同時也能有效阻斷NGF對傷害性離子通道/受體的活性和傷害性基因表達水平的調節作用,減輕傷害性疼痛,從而發揮治療疼痛的作用。
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