康寧傑瑞製藥-B(09966.HK)將於歐洲腫瘤內科學會大會上展示KN046及KN026研究進展
康寧傑瑞製藥-B(09966.HK)公布,KN046及KN026六個不同的研究進展將以摘要及壁報形式於2023年歐洲腫瘤內科學會大會(2023年ESMO大會)上展示。2023年ESMO大會將於10月20至24日(當地時間)於西班牙馬德里舉行。KN046及KN026的研究進展亦將於公司網站相應公布。
KN046是集團自主研發的全球性首創PD-L1/CTLA-4雙特異性抗體,同時靶向具有明顯結構差異的PD-L1及CTLA-4,可改變腫瘤微環境的定位及減少脫靶毒性。KN046的臨床前及臨床試驗結果展現出良好的療效,並表明可顯著減少對人體外周系統的毒副作用。公司認為,KN046有望成為突破性腫瘤免疫特效藥。
KN026旨在成為全球性新一代HER2靶向療法。目前,KN026作為二線或以上療法治療HER2陽性GC/GEJ及作為一線療法治療HER2陽性乳腺癌的兩項III期臨床試驗正在中國進行。
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