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吉貝爾(688566.SH):公司正有序推進JJH201601開展I期臨牀研究
格隆匯 07-28 16:01

格隆匯7月28日丨有投資者向吉貝爾(688566.SH)提問:請介紹下公司抗腫瘤一類新藥JJH201601研發進展?

吉貝爾回覆:公司在研抗腫瘤新藥JJH201601是通過分子設計和藥效試驗篩選,得到的全新化合物,並依託脂質體藥物研發技術平台開發的一類抗腫瘤新藥。研究表明,注射用JJH201601脂質體在多種實體瘤CDX模型上的抑瘤作用顯著,且均強於進口多西他賽注射液(商品名:泰索帝),並具有更低的毒副作用。同時,在多項由重度免疫缺陷小鼠構建的PDX荷瘤模型上,JJH201601也表現出優於陽性對照多西他賽、白蛋白紫杉醇、替吉奧和吉西他濱的抑瘤效果,且藥物的耐受性和安全性較好。目前JJH201601已取得《藥物臨牀試驗批准通知書》,批准本品單藥在晚期實體瘤中開展臨牀試驗,公司正有序推進JJH201601開展I期臨牀研究。

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