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金斯瑞(01548.HK)附屬傳奇生物終止LB1901新藥臨牀試驗
金斯瑞生物科技(01548.HK)公佈,附屬傳奇生物通知美國食品藥品監督管理局(FDA),其已終止針對LB1901的新藥臨牀試驗申請的I期臨牀試驗,原因是傳奇生物一款與LB1901表達相同CAR蛋白的類似CAR-T候選產品缺乏臨牀效益。 LB1901爲傳奇生物在研的自體嵌合抗原受體T細胞(CAR-T)療法,用於治療複發性或難治性T細胞淋巴瘤成人患者。
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