翰森製藥(03692.HK):與NiKang Therapeutics訂立許可協議
格隆匯5月2日丨翰森製藥(03692.HK)宣佈,於美國東部時間2022年5月2日,公司全資附屬公司翰森(上海)健康科技有限公司及江蘇豪森藥業集團有限公司(統稱為"被許可人")與NiKang Therapeutics Inc.("NiKang Therapeutics")訂立獨家許可協議。
根據許可協議,被許可人獲得NiKang Therapeutics的獨家許可,以於中國開發及商業化NKT2152用於腫瘤的治療。被許可人將負責NKT2152於中國的開發、註冊審批及商業化,並將支付1,500萬美元首付款及最多2.03億美元的開發、註冊及基於銷售的商業化里程碑潛在付款,以及基於淨銷售額的分級特許權使用費。
NKT2152是一種抑制HIF-2α的小分子,目前正開展1/2期劑量遞增及擴展試驗(NCT05119335)。該試驗旨在評估對晚期透明細胞腎細胞癌(ccRCC)患者的安全性、耐受性、藥代動力學、藥效學及臨牀活性。
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