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開拓藥業-B(9939.HK)盤中一度大漲近40%
格隆匯 02-07 11:55
格隆匯2月7日丨開拓藥業-B(9939.HK)高開高走,盤中一度大漲近40%至11.14港元。開拓藥業2月3日宣佈,GT20029治療脱髮和痤瘡美國I期臨牀試驗已於當地時間2022年2月1日完成首例受試者入組及給藥。該臨牀試驗是一項隨機、雙盲、安慰劑對照、平行設計、劑量遞增的研究,以評估GT20029(凝膠)在健康受試者中單次劑量遞增和在雄激素性脱髮或痤瘡受試者中多次劑量遞增後的安全性、耐受性和藥代動力學(PK)等特徵。GT20029是使用集團自主開發的靶向蛋白降解嵌合體(“PROTAC”)平台開發的首款雄激素受體(“AR”)化合物。據公司所知,它是全球首個進入臨牀階段的外用PROTAC化合物。

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