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藥明巨諾-B(02126.HK)披露治療淋巴瘤藥物「倍諾達」主要臨床效果
阿思達克 12-13 09:58
藥明巨諾-B(02126.HK)公布,在第63屆美國血液學會年會上公布倍諾達(瑞基奧侖賽注射液)用於治療復發/難治性(r/r)濾泡淋巴瘤(FL)中國成人患者中的主要臨床效果。 到數據截至日9月10日,共有28例復發/難治性濾泡淋巴瘤中國成人患者接受了倍諾達的治療,並達到至少3個月的隨訪期。在27例可評估有效性的患者中,基於研究者評估的最佳客觀緩解率(ORR)為100%(27/27),最佳完全緩解率(CRR)為92.6%(25/27)。中位隨訪時間8.84個月,未達到中位緩解持續時間(DOR)、中位無進展生存期(PFS)及中位總生存期(OS)。 在接受倍諾達治療的28例患者中,所有級別及重度細胞因子釋放綜合症(CRS)的發生率分別為42.9%及0%,所有級別及重度神經毒性(NT)的發生率分別為17.9%及3.6%。
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