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上海醫藥(601607.SH):與Phagelux公司就抗細菌感染新藥ClyO項目進行合作
格隆匯 11-04 16:51

格隆匯11月4日丨上海醫藥(601607.SH)發佈,近日,公司全資子公司上海上藥新亞藥業有限公司(“上藥新亞”)與Phagelux. Inc.(簡稱“Phagelux”)簽訂《合作協議》,以不超過美元(幣種下同)5050萬(除銷售提成外)的交易金額取得抗細菌感染新藥ClyO項目在中國大陸、香港與澳門的研發、生產、註冊、經銷、銷售、營銷、推廣和再許可的權利,包含ClyO的針對金葡菌導致的系統性感染適應症。

ClyO是一款新型作用機制的抗葡萄球菌屬細菌的噬菌體裂解酶,為大腸桿菌發酵生產的重組多肽藥物,目前針對金葡菌導致的系統性感染適應症正處於臨牀前研究階段。相對噬菌體,裂解酶的上市註冊路徑更為明確;相對傳統抗生素,ClyO體外殺菌強力速效,不易產生耐藥性,且僅針對葡萄球菌屬細菌,對正常菌羣不會產生不良影響。

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