翰森製藥(03692.HK)訂獨家許可合作協議 支付1,600萬美元預付款
翰森製藥(03692.HK)公布,與Silence Therapeutics(SLN.US)訂立獨家許可合作協議,根據協議,公司及Silence Therapeutics將利用後者的獨家mRNAi GOLD平台,以合作開發針對三個靶點的短干擾RNA。對於首兩個靶點,在完成一期臨床研究後,公司將擁有在中國的許可的獨家選擇權,Silence Therapeutics將擁有該地域以外其他地區的獨家權益。
Silence Therapeutics將負責許可權行使之前的所有活動,並將對該地域以外的首兩個靶點的一期臨床後開發負責。對於第三個靶點,公司將於新藥臨床試驗申報時獲得全球權利許可的獨家選擇權,公司並將負責第三個靶點選擇權行使後的所有開發活動。
公司將向Silence Therapeutics支付1,600萬美元預付款,並在達到額外的開發、監管和商業里程碑後合資格獲得高達13億美元,Silence Therapeutics並將獲得公司產品淨銷售額約10%至15%區間的特許權使用費。
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