歌禮製藥(01672.HK)附屬肝臟靶向性前體藥物臨床試驗獲良好頂線數據
歌禮製藥(01672.HK)公布,旗下全資附屬甘萊製藥的肝臟靶向性前體藥物ASC41口服片劑健康受試者藥物相互作用和非酒精性脂肪性肝病(NAFLD)患者藥代動力學(PK)美國I期臨床試驗取得良好頂線數據。
ASC41主要通過CYP3A4代謝形成活性代謝物ASC41-A,ASC41-A是一種選擇性甲狀腺激素β受體(THRβ)激動劑。
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