歌礼制药-B(01672.HK):甘莱FXR激动剂ASC42完成美国I期临床试验首例受试者给药
格隆汇 12 月 28日丨歌礼制药-B(01672.HK)发布公告,公司全资附属公司甘莱制药有限公司(“甘莱”)的法尼醇X受体(FXR)激动剂、NASH候选药物ASC42的美国I期临床试验已完成首例受试者给药。
该I期临床试验是一项在美国开展的随机、双盲、安慰剂对照、单剂量与多剂量递增研究,旨在评估ASC42在健康受试者中的安全性、耐受性、药代动力学和药效动力学特征(生物标志物-FGF19和C4)。该试验还研究了食物对ASC42暴露量的影响。
ASC42是一种由甘莱完全自主研发的新型高效选择性非甾类FXR激动剂。ASC42作为NASH候选药物已于近日获得美国食品药品监督管理局(FDA)的快速通道资格认定。ASC42口服片剂由甘莱专有制剂技术开发,具有室温下稳定的特点。
Follow us
Find us on
Facebook,
Twitter ,
Instagram, and
YouTube or frequent updates on all things investing.Have a financial topic you would like to discuss? Head over to the
uSMART Community to share your thoughts and insights about the market! Click the picture below to download and explore uSMART app!

Disclaimers
uSmart Securities Limited (“uSmart”) is based on its internal research and public third party information in preparation of this article. Although uSmart uses its best endeavours to ensure the content of this article is accurate, uSmart does not guarantee the accuracy, timeliness or completeness of the information of this article and is not responsible for any views/opinions/comments in this article. Opinions, forecasts and estimations reflect uSmart’s assessment as of the date of this article and are subject to change. uSmart has no obligation to notify you or anyone of any such changes. You must make independent analysis and judgment on any matters involved in this article. uSmart and any directors, officers, employees or agents of uSmart will not be liable for any loss or damage suffered by any person in reliance on any representation or omission in the content of this article. The content of the article is for reference only and does not constitute any offer, solicitation, recommendation, opinion or guarantee of any securities, virtual assets, financial products or instruments. Regulatory authorities may restrict the trading of virtual asset-related ETFs to only investors who meet specified requirements. Any calculations or images in the article are for illustrative purposes only.
Investment involves risks and the value and income from securities may rise or fall. Past performance is not indicative of future performance. Please carefully consider your personal risk tolerance, and consult independent professional advice if necessary.