眾生藥業(002317.SZ):控股子公司一類創新藥RAY1225注射液減重Ⅱ期臨牀試驗獲得子研究頂線分析數據結果
格隆匯11月20日丨眾生藥業(002317.SZ)公佈,公司控股子公司廣東眾生睿創生物科技有限公司(以下簡稱“眾生睿創”)自主研發的一類創新多肽藥物RAY1225注射液用於超重/肥胖患者的Ⅱ期臨牀試驗,於近日獲得子研究的頂線分析數據。初步結果表明,RAY1225注射液在中國成人超重/肥胖參與者中表現出積極的療效和良好的安全性,試驗結果理想,達到預期目的。
RAY1225注射液是眾生睿創研發的、具有全球自主知識產權的創新結構多肽藥物,屬於長效GLP-1類藥物,具有GLP-1受體和GIP受體雙重激動活性。
RAY1225注射液用於肥胖/超重患者與2型糖尿病患者的兩項Ⅱ期臨牀研究仍在進行中。用於肥胖/超重患者的Ⅱ期臨牀試驗(REBUILDING-1)於近日完成PartA子研究的數據庫清理和鎖定,獲得頂線分析結果,達到主要終點,並在減重達標率和多種心血管和代謝危險因素改善方面均顯著優於安慰劑。
眾生睿創繼續積極推進RAY1225注射液較高劑量9mg、12mg和15mg的擴展研究,以獲得RAY1225注射液用於超重/肥胖參與者的更多有效性和安全性數據。
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