金斯瑞生物科技(01548.HK):申辦研究的八篇摘要已入選2022年ASCO年會和2022年EHA線上線下混合會議
格隆匯5月18日丨金斯瑞生物科技(01548.HK)公吿,傳奇生物科技股份有限公司(為公司非全資附屬公司,其股份以美國存托股份形式於美國納斯達克全球精選市場上市)宣佈,公司申辦研究的八篇摘要已入選2022年美國臨牀腫瘤學會(ASCO)年會(2022年ASCO年會)和2022年歐洲血液學協會(EHA)線上線下混合會議(2022年EHA線上線下混合會議)。
這些報吿將提供CARTITUDE臨牀開發計劃的最新資料,該項目旨在評估西達基奧侖賽(CARVYKTI, cilta-cel)用於多發性骨髓瘤治療的安全有效性,西達基奧侖賽是一種靶向B細胞成熟抗原(BCMA)的嵌合抗原受體T細胞(CAR-T)療法。
CARTITUDE-1長期(末例患者入組後兩年)隨訪結果將在2022年ASCO年會和2022年EHA線上線下混合會議上以海報形式呈現。CARTITUDE-1是一項針對既往接受過多線治療的復發或難治性多發性骨髓瘤(R/R MM)患者的1b/2期研究,其結果支持了美國食品藥品監督管理局(FDA)對CARVYKTI的批准。
報吿還將呈現CARTITUDE-2研究隊列A和隊列B的更新資料。該項多隊列研究旨在評估西達基奧侖賽在多發性骨髓瘤的各種治療場景(包括前線治療)中的安全性和有效性。隊列A包括既往接受過1–3線治療後出現進展且對來那度胺耐藥的多發性骨髓瘤患者,其資料將在2022年ASCO年會和2022年EHA線上線下混合會議上以海報形式呈現。隊列B包括在初始治療(包括蛋白酶體抑制劑和免疫調節劑藥物)後出現早期復發的患者,其資料將在2022年ASCO年會上以海報展示,並在2022年EHA線上線下混合會議上以口頭報吿的形式呈現。其他資料也將在這兩次會議上公佈,包括來自真實世界研究LocoMMotion的資料,該研究是一項在常規臨牀實踐中針對R/R MM患者進行真實世界標準治療的前瞻性跨國研究。
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