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绿叶制药(02186.HK)就中枢神经领域新药在美国提交临床试验申请
阿思达克 08-02 08:32
绿叶制药(02186.HK)公布,已就其中枢神经领域新药LY03015向美国食品药品监督管理局提交临床试验(IND)申请。LY03015为集团自主研发的治疗迟发性运动障碍(TD)和亨廷顿舞蹈病(HD)的创新小分子化合物产品。

LY03015是新一代VMAT2抑制剂,可通过抑制突触前神经元多巴胺(DA)的释放,避免DA对超敏D2受体刺激的同时也不阻滞突触后膜的D2受体,从而减轻迟发性运动障碍和亨廷顿舞蹈病的症状。

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