恆瑞醫藥(600276.SH)獲藥物臨牀試驗批准通知書
格隆匯7月22日丨恆瑞醫藥(600276.SH)公佈,公司及子公司蘇州盛迪亞生物醫藥有限公司、上海恆瑞醫藥有限公司近日收到國家藥監局核准簽發的《藥物臨牀試驗批准通知書》,並將於近期開展臨牀試驗。
注射用SHR-A1811可通過與HER2表達的腫瘤細胞結合並內吞,在腫瘤細胞溶酶體內通過蛋白酶剪切釋放毒素,誘導細胞週期阻滯從而誘導腫瘤細胞凋亡,擬用於治療HER2表達或突變的晚期實體瘤。截至目前,該產品累計已投入研發費用約為4160萬元。
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