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科倫博泰生物-B(06990.HK):默沙東已啟動三項關鍵3期臨床試驗 觸發7,500萬美元臨床里程碑款項
科倫博泰生物-B(06990.HK)公布,默沙東已啟動三項關鍵3期臨床試驗,評估SKB264(MK-2870)作為單藥用於治療既往接受過治療的具有表皮生長因子受體(EGFR)突變或其他基因組改變的晚期或轉移性非小細胞肺癌(NSCLC),作為單藥用於治療既往接受含鉑化療及免疫治療的子宮內膜癌(EC),以及與帕博利珠單抗聯合用於程序性死亡配體1(PD-L1)表達大於或等於50%的轉移性NSCLC。 根據許可及合作協議以及默沙東的書面確認,上述NSCLC及EC的臨床試驗已觸發相關臨床里程碑付款,總金額為7,500萬美元。公司已收到默沙東的部分付款,並預計在不久的將來收到餘下款項。
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