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仙琚製藥(002332.SZ):收到潑尼鬆龍片、氟馬西尼注射液一致性評價受理通知書
格隆匯 09-18 17:34

格隆匯 9 月 18日丨仙琚製藥(002332.SZ)公佈,公司於近日收到國家藥品監督管理局下發的潑尼鬆龍片、氟馬西尼注射液一致性評價受理通知書。

潑尼鬆龍是一種常見的皮質類固醇,廣泛用於抗炎和免疫抑制。它是一種人工合成的強效糖皮質激素,是其前藥潑尼鬆的活性代謝物。潑尼鬆龍已被列入WHO 基本藥物清單。與氫化可的鬆相比,潑尼鬆龍在治療各種急性和慢性疾病,包括哮喘、肝炎、關節炎、系統性紅斑狼瘡和過敏性皮膚病中表現出更高的抗炎活性和更低的鈉瀦留。

氟馬西尼是選擇性γ-氨基丁酸A型受體(GABAA)拮抗劑,通過競爭性抑制γ-氨基丁酸-苯二氮複合物(GABA-BDZ)識別BDZ受體藥物,進而減少γ-氨基丁酸(GABA)的釋放,逆轉GABA釋放帶來的中樞抑制作用,臨牀上主要用於拮BDZ受體激動產生的各種症狀。

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